Imipenem resistant metallo β lactamse producingPseudomonas aeruginosa

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Imipenem Resistant Metallo β Lactamse Producing Pseudomonas aeruginosa Phenotypic Expression of Methicillin Resistance in Nosocomial Staphylococcus aureus

Pseudomonas aeruginosa, an important nosocomial pathogen is difÞ cult to treat because of high antimicrobial resistance.[1] The common form of resistance is mediated by lack of drug penetration and / or carbapenem hydrolyzing ß-lactamases.[2] Detection of metallo ß lactamase (MBL)producing P. aeruginosa is crucial for the optimal treatment of patients. The present study was undertaken to study ...

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Phenotypic Detection of Metallo-β-Lactamase in Imipenem-Resistant Pseudomonas aeruginosa

Carbapenems are the primary choice of treatment for severe Pseudomonas aeruginosa infection. However, the emergence of carbapenem resistance due to the production of metallo-β-lactamases (MBLs) is of global concern. In this study, 90 imipenem- (IPM- or IP-) resistant P. aeruginosa (IRPA) isolates, including 32 previously tested positive and genotyped for MBL genes by PCR, were subjected to doub...

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Antimicrobial Effect of Imipenem-Functionalized Fe2O3 Nanoparticles on Pseudomonas aeruginosa Producing Metallo β-lactamases

Background: Resistant strains of Pseudomonas aeruginosa to imipenem was medical treatment problem, especially in burnt units of hospitals. Objectives: This study was conducted to evaluate the antimicrobial effect of Fe2O3 nanoparticles alone and functionalized with imipenem on P. aeruginosa starins producing metallo b-lactamases (MBL). Materials and Methods: A disk diffusion method was used to...

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Nosocomial outbreak of imipenem-resistant Pseudomonas aeruginosa producing VIM-2 metallo-β-lactamase in a kidney transplantation unit

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ژورنال

عنوان ژورنال: Indian Journal of Medical Microbiology

سال: 2008

ISSN: 0255-0857

DOI: 10.4103/0255-0857.43565